EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

Read More..

Israel bombards Gaza Strip, shoots down rocket

GAZA CITY, Gaza Strip (AP) — Israel destroyed the headquarters of Hamas' prime minister and blasted a sprawling network of smuggling tunnels in the southern Gaza Strip on Saturday, broadening a blistering four-day-old offensive against the Islamic militant group even as diplomatic efforts to broker a cease-fire appeared to be gaining steam.

In neighboring Egypt, President Mohammed Morsi hosted leaders from Hamas and two key allies, Qatar and Turkey, to seek a way to end the fighting.

"There are discussions about the ways to bring a cease-fire soon, but there are no guarantees until now," Morsi said at a news conference. He said he was working with Turkey, Arab countries, the U.S., Russia and western European countries to halt the fighting.

Israel launched the operation on Wednesday in what it said was an effort to end months of rocket fire out of the Hamas-ruled territory. It began the offensive with an unexpected airstrike that killed Hamas' powerful military chief, and since then has relentlessly targeted suspected rocket launchers and storage sites.

In all, 46 Palestinians, including 15 civilians, have been killed and more than 400 civilians wounded, according to medical officials. Three Israeli civilians have been killed and more than 50 wounded.

Israeli military officials expressed satisfaction with their progress Saturday, claiming they have inflicted heavy damage to Hamas.

"Most of their capabilities have been destroyed," Maj. Gen. Tal Russo, Israel's southern commander, told reporters. Asked whether Israel is ready to send ground troops into Gaza, he said: "Absolutely."

The White House said President Barack Obama was also in touch with the Egyptian and Turkish leaders. The U.S. has solidly backed Israel so far.

Speaking on Air Force One, deputy national security adviser Ben Rhodes said that the White House believes Israel "has the right to defend itself" against attack and that the Israelis will make their own decisions about their "military tactics and operations."

The White House, which like Israel considers Hamas a terrorist organization, also continued to support Israel. "We believe Israel has a right to defend itself, and they'll make their own decisions about the tactics they use in that regard," deputy national security adviser Ben Rhodes told reporters on Air Force One.

Despite the bruising offensive, Israel has failed to slow the barrages of rockets from Gaza.

The Israeli military said 160 rockets were launched into Israel on Saturday, raising the total number to roughly 500 since this week's fighting began. Eight Israelis, including five civilians, were lightly wounded Saturday, the army said.

Israel carried out at least 300 airstrikes on Saturday, the military said, and it broadened its array of targets. One air raid flattened the three-story office building used by Hamas' prime minister, Ismail Haniyeh. He was not inside the building at the time.

In southern Gaza, aircraft went after the tunnels that militants use to smuggle in weapons and other contraband from neighboring Egypt. Tunnel operators said the intensity of the bombing was unprecedented, and that massive explosions could be heard kilometers (miles) away, both in Gaza and in Egypt.

The operators, speaking on condition of anonymity because of the illicit nature of their business, said they cannot approach the tunnel area to assess the damage, but the blasts appeared to be more powerful than in Israel's last major push to destroy the tunnels during a previous offensive four years ago. The tunnels are a key lifeline for Hamas, bringing in both weapons and supporting a lucrative trade that helps fund the group's activities.

Missiles also smashed into two small security facilities and the massive Hamas police headquarters in Gaza City, setting off a huge blaze that engulfed nearby houses and civilian cars parked outside, the Interior Ministry reported. No one was inside the buildings.

Air attacks knocked out five electricity transformers, cutting off power to more than 400,000 people in southern Gaza, according to the Gaza electricity distribution company. People switched on backup generators for limited electrical supplies.

Hamas has unveiled an arsenal of more powerful, longer-range rockets this week, and for the first time has struck at Israel's two largest cities, Jerusalem and Tel Aviv. Both cities, more than 70 kilometers (45 miles) from Gaza, had previously been beyond rocket range.

In a psychological boost for Israel, a new rocket-defense system known as "Iron Dome" knocked down a rocket headed toward Tel Aviv, eliciting cheers from relieved residents huddled in fear after air raid sirens sounded in the city.

Associated Press video showed a plume of smoke following an intercepting missile out of a rocket-defense battery deployed near the city, followed by a burst of light overhead as it struck its target.

Police said a second rocket also targeted Tel Aviv. It was not clear where it landed or whether it was shot down. No injuries were reported. It was the third straight day the city was targeted.

Israel says the Iron Dome system has shot down some 250 of 500 rockets fired toward the country this week, most in southern Israel near Gaza.

Saturday's interception was the first time Iron Dome has been deployed in Tel Aviv. The battery was a new upgraded version that was only activated on Saturday, two months ahead of schedule, the Defense Ministry said.

Israel has vowed to stage a ground invasion, a scenario that would bring the scale of fighting closer to that of a war four years ago. Hamas was badly bruised during that conflict but has since restocked its arsenal with more and better weapons. Five years after seizing control of Gaza, it has also come under pressure from smaller, more militant groups to prove its commitment to fighting Israel as it turns its focus to governing the seaside strip.

Israel's Defense Minister Ehud Barak has authorized the emergency call-up of up to 75,000 reserve troops ahead of a possible ground offensive. Israel has massed thousands of troops and dozens of tanks and armored vehicles along the border in recent days.

Egypt, which is led by Hamas' parent movement, the Muslim Brotherhood, has been spearheading efforts to forge a cease-fire. Morsi has vowed to stand strong with the people of Gaza and this week recalled Cairo's ambassador from Israel to protest the offensive.

Quietly, though, non-Muslim Brotherhood members in Morsi's government are said to be pushing Hamas to end its rocket fire on Israel. Morsi is under pressure not to go too far and risk straining ties with Israel's ally, the United States.

The Hamas website said Saturday that its leader, Khaled Meshaal, met with the head of Egyptian intelligence for two hours Saturday in Cairo, a day after the Egyptian official was in the Gaza Strip trying to work out an end to the escalation in violence.

Hamas has not immediately accepted Egypt's proposal for a cease-fire, but the group's website said it could end its rocket fire if Israel agrees to end "all acts of aggression and assassination" and lift its five-year Israeli blockade on Gaza. Egypt will present the Hamas position to Israeli officials.

Israeli officials say they are not interested in a "timeout," and want firm guarantees that the rocket fire, which has paralyzed life in an area home to 1 million Israelis, finally ends. Past cease-fires have been short lived.

Israeli Prime Minister Benjamin Netanyahu said he spoke with the leaders of Britain, Poland, Portugal, Bulgaria to press his case. "No government in the world would allow a situation where its population lives under the constant threat of rockets," Netanyahu told them, according to a statement from his office.

The diplomatic activity in Cairo illustrated Hamas' rising influence in a changing Middle East. The Arab Spring has brought Islamists to power and influence across the region, helping Hamas emerge from years of isolation.

Morsi warned that a ground operation by Irael will have "repercussions" across the region. "All must realize the situation is different than before, and the people of the region now are different than before and the leaders are different than before," he said at a joint press conference with Turkey's Islamist prime minister, Recep Tayyip Erdogan. Erdogan, like Morsi, leads an Islamist government that has chilly diplomatic ties with Israel.

On Friday, Morsi sent his prime minister to Gaza on a solidarity mission with Hamas. And on Saturday, Tunisia's Foreign Minister Rafik Abdessalem visited Gaza as well.

___

Federman reported from Jerusalem. Associated Press writers Karin Laub in Gaza City and Aya Batrawy in Cairo contributed reporting.

Read More..

Pakistan releases son of Afghan militant leader

PESHAWAR, Pakistan (AP) — The son of a legendary Afghan mujahedeen leader was among a group of Taliban prisoners released by Pakistan to help jumpstart peace negotiations with the militant group, the man's cousin and a family friend said Friday.

The decision to release the prisoners is seen as a signal to neighboring Afghanistan that Pakistan might be willing to take concrete steps to revive efforts to lure the group to the negotiating table.

Pakistan released Anwarul Haq Mujahid on Thursday, and he joined his family in the northwestern Pakistani city of Peshawar, said the cousin and family friend, speaking on condition of anonymity because they were not authorized to talk to the media.

Mujahid is the son of the late Maulvi Mohammad Yunus Khalis who fought against the Soviets in Afghanistan in the 1980s. Khalis, who was once invited to the White House by former President Ronald Regan, died in 2006.

Afghan officials said Thursday that Pakistan freed eight Taliban prisoners and agreed to release many more. Mujahid was not among the eight listed by the Afghan officials, which means at least nine prisoners have been freed.

The most prominent prisoner freed was former Justice Minister Nooruddin Turabi who served when the Taliban ruled Afghanistan.

The U.S. and its allies fighting in Afghanistan are pushing to strike a peace deal with the Taliban so they can withdraw most of their troops by the end of 2014. The prisoner release could help, but considerable obstacles remain. It is unclear whether the Taliban even intend to take part in the process, rather than just wait until foreign forces withdraw.

Pakistan is seen as key to the peace process. Islamabad has ties to the Taliban that date back to the 1990s, and many of the group's leaders are believed to be based on Pakistani territory, having fled there following the U.S.-led invasion of Afghanistan in 2001.

Also Friday, a Pakistani lawyer accused the military of sending thugs to beat him up after he challenged the army chief in court.

Inam Ur Raheem, a retired military lawyer, said three vehicles surrounded his taxi Wednesday night in the garrison city of Rawalpindi. Several unidentified men jumped out and attacked him with sticks, leaving him with cuts and bruises. He claimed they said they were there to teach him a lesson.

The attack came a day after Raheem filed a petition in the Islamabad High Court challenging the validity of a three-year extension given to army chief Gen. Ashfaq Parvez Kayani in 2010.

The army denied any role in the attack Friday, calling Raheem's allegations baseless.

The New York Times first reported the attack Thursday.

____

Associated Press writer Munir Ahmed contributed to this report from Islamabad.

Read More..

Pittsburgh airport to offer free ‘cell phone’ lot
















IMPERIAL, Pa. (AP) — Pittsburgh International Airport is offering free parking for folks who want to sit in their cars and wait for arriving passengers to call on cell phones to say they’ve arrived.


Allegheny County Airport Authority officials are hoping the plan will prevent motorists from congesting the curb near the airport’s terminal or the access roads around it by driving around in circles waiting for cell phone calls from arrivals.













Drivers can now park free for an hour in the extended term lot farthest from the terminal, and pay only $ 1 for a second hour of parking. After two hours, the spots will cost $ 8.


Gadgets News Headlines – Yahoo! News



Read More..

Pitbull, Ke$ha rehearse for American Music Awards

LOS ANGELES (AP) — Pitbull dressed up and Ke$ha went casual for American Music Awards rehearsals.

The entertainers popped by the Nokia Theatre Friday to practice the performances they've planned for Sunday's show.

Ke$ha was surrounded by male dancers as she bounced around the stage in sneakers, striped leggings and a torn black T-shirt. She played a giant golden drum, was carried aloft by her dancers and closed the rendition of her new hit "Die Young" by writhing on stage as fireworks rained down overhead.

Pitbull, fresh off his performance at Thursday's Latin Grammy Awards, arrived wearing crisp white pants, a red polo shirt and a tan blazer. After joking with his band in Spanish, he ditched the blazer and added shades to rehearse "Don't Stop the Party," for which he shares the stage with two drummers, two keyboardists, two ballerinas and a DJ.

Justin Bieber, Kelly Clarkson, Usher, Carrie Underwood, Taylor Swift, No Doubt, Christina Aguilera and Nicki Minaj are also set to perform during the three-hour ceremony, which will be broadcast live Sunday on ABC.

Stevie Wonder and Ryan Seacrest will also honor the late Dick Clark, who created the American Music Awards, at the 40th anniversary show.

___

AP Entertainment Writer Sandy Cohen will be tweeting from the American Music Awards. Follow her at www.twitter.com/APSandy .

___

Online:

http://beta.abc.go.com/shows/american-music-awards

Read More..

EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

Read More..

Israelis, Palestinians lob threats via Twitter

Poaching and trafficking -- a menace for already endangered animals http://t.co/IO6vY4uc
Read More..

PM to dissolve Japan's parliament, call elections

TOKYO (AP) — Prime Minister Yoshihiko Noda is poised to dissolve Japan's parliament, setting the stage for elections next month that will likely end the ruling Democrats' three years in power.

Polls suggest that the opposition Liberal Democratic Party, which led Japan for most of the post-World War II era, would win the most seats in the 480-seat lower house, but far short of a majority.

It is likely that no party will emerge as a clear winner in the lower house election and the party would have to form a coalition to govern. Reports say polls would be set for Dec. 16.

Noda abruptly said Wednesday he would dissolve parliament on Friday if the opposition would agree to key reforms, including shrinking the size of parliament.

Read More..

Andre 3000 isn't in a rush to record new album

NEW YORK (AP) — In order to capture his best version of Jimi Hendrix for an upcoming biopic, Andre 3000 said he had to think of him as a regular dude and not a rock star.

"I didn't look at him as an icon because when you're in it, you don't know you're an icon. You don't know you're an icon until another people say you're an icon," the 37-year-old said in an interview Tuesday.

"So I had to take it as a person, you know what I mean? And I just tried to say, 'Well, what would Jimi want people to know that they can't get off of YouTube?' And that's how I approached it," he said.

Hendrix died at age 27 in 1970. He was ranked No. 1 on Rolling Stone magazine's greatest guitarists of all-time list. His band, The Jimi Hendrix Experience, is known for iconic albums such as "Electric Ladyland" and "Are You Experienced."

"All Is by My Side," which focuses on the early days of Hendrix's career, will be released next year. Andre 3000 is excited to see the film, which he's finished shooting in Ireland. He believes the public "will be pleased."

Andre 3000, one-half of OutKast with Big Boi, has been out of the music scene in recent years, although he's been featured on songs by Beyonce, Frank Ocean, Rick Ross, Ke$ha and Young Jeezy.

OutKast's 2006 platinum-selling album, "Idlewild," which accompanied a film of the same name starring the duo, was their last album. Their 11-time platinum "Speakerboxxx/The Love Below" won the 2004 Grammy Award for album of the year.

Big Boi, who released a solo album two years ago to welcoming reviews, will release a new solo disc, "Vicious Lies and Dangerous Rumors," next month.

But Andre 3000 isn't in a rush to record an album.

"Some days I feel like I'll do it, some days I don't. Some days I feel like I don't need to, some days I feel like I want to do it before I die. So, I don't know where to fall. I am just hoping one day I get that inspiration," he said at an event for Gillette's eMO'gency Styler Tour, which supports men's health and prostate cancer programs. The tour kicked off in New York, with stops scheduled in Chicago and Houston.

"It's a feeling for me. Like, I can't just throw out an album to be rapping," he said. "And I don't even know if it will be rap. I don't even know what it will be."

However, he could find the inspiration and complete an album in just a few days: "It could be a rush situation. Like if I feel that feeling and I record an album in three days and I'm like, 'This is what I want to say right now' — that can happen, too."

He also says he's constantly writing songs.

"I write all the time. ... I actually stopped typing it in my phone because like a cloud is basically reading every thought that I have and I don't like that," he said. "So I went back to my paper and started writing."

He's not sure fans want a new OutKast album for the right reasons.

"Man, we've had a great ride. ... Like when we got into it when we were high school kids and we just wanted to do something fun and push it, and if it's not that then why do it?" he said.

"I'm not the type that prescribes to nostalgia, and most people say they want an OutKast album because they used to love it. Y'all don't even know if y'all still love it. You just know you used to love it. But you may not like it now, who knows?"

___

Follow Mesfin Fekadu on Twitter at http://twitter.com/musicmesfin

Read More..

Diabetes rates rocket in Oklahoma, South

NEW YORK (AP) — The nation's diabetes problem is getting worse, and the biggest jump over 15 years was in Oklahoma, according to a new federal report issued Thursday.

The diabetes rate in Oklahoma more than tripled, and Kentucky, Georgia and Alabama also saw dramatic increases since 1995, the study showed.

The South's growing weight problem is the main explanation, said Linda Geiss, lead author of the report by the Centers for Disease Control and Prevention study.

"The rise in diabetes has really gone hand in hand with the rise in obesity," she said.

Bolstering the numbers is the fact that more people with diabetes are living longer because better treatments are available.

The disease exploded in the United States in the last 50 years, with the vast majority from obesity-related Type 2 diabetes. In 1958, fewer than 1 in 100 Americans had been diagnosed with diabetes. In 2010, it was about 1 in 14.

Most of the increase has happened since 1990.

Diabetes is a disease in which the body has trouble processing sugar; it's the nation's seventh leading cause of death. Complications include poor circulation, heart and kidney problems and nerve damage.

The new study is the CDC's first in more than a decade to look at how the nationwide boom has played out in different states.

It's based on telephone surveys of at least 1,000 adults in each state in 1995 and 2010. Participants were asked if a doctor had ever told them they have diabetes.

Not surprisingly, Mississippi — the state with the largest proportion of residents who are obese — has the highest diabetes rate. Nearly 12 percent of Mississippians say they have diabetes, compared to the national average of 7 percent.

But the most dramatic increases in diabetes occurred largely elsewhere in the South and in the Southwest, where rates tripled or more than doubled. Oklahoma's rate rose to about 10 percent, Kentucky went to more than 9 percent, Georgia to 10 percent and Alabama surpassed 11 percent.

An official with Oklahoma State Department of Health said the solution is healthier eating, more exercise and no smoking.

"And that's it in a nutshell," said Rita Reeves, diabetes prevention coordinator.

Several Northern states saw rates more than double, too, including Washington, Idaho, Montana, Wyoming, South Dakota, Minnesota, Missouri, Ohio and Maine.

The study was published in CDC's Morbidity and Mortality Weekly Report.

___

Associated Press writer Ken Miller in Oklahoma City contributed to this report.

___

Online:

CDC report: http://tinyurl.com/cdcdiabetesreport

Read More..