Personal, strategic motivations for Obama in Asia

BANGKOK (AP) — For President Barack Obama, expanding U.S. influence in Asia is more than just countering China or opening up new markets to American businesses. It's also about building his legacy.

Fresh off re-election, Obama will make a significant investment in that effort during a quick run through Southeast Asia that begins Sunday. In addition to stops in Thailand and Cambodia, the president will make a historic visit to Myanmar, where his administration has led efforts to ease the once pariah nation out of international isolation.

The trip marks Obama's fourth visit to Asia in as many years. He kicks off his schedule in Bangkok. With a second term now guaranteed, aides say Obama will be a regular visitor to the region over the next four years as well.

"Continuing to fill in our pivot to Asia will be a critical part of the president's second term and ultimately his foreign policy legacy," said Ben Rhodes, Obama's deputy national security adviser.

The president's motivations in Asia are both personal and strategic.

Obama, who was born in Hawaii and lived in Indonesia as a child, has called himself America's first "Pacific president." The region gives him an opportunity to open up new markets for U.S. companies, promote democracy and ease fears of China's rise by boosting U.S. military presence in area.

The president, like many of his predecessors, had hoped to cement his foreign policy legacy in the Middle East. He visited two major allies in the region, Egypt and Saudi Arabia, on one of his first overseas trips as president and attempted to revive peace talks between Israel and the Palestinians.

But those talks stalled, and fresh outbursts of violence between Israel and the Palestinians make the prospects of a peace accord appear increasingly slim. The Obama-backed Arab Spring democracy push has had mixed results so far, with Islamists taking power in Egypt and progress in Libya tainted by the deadly attacks on the U.S. Consulate in Benghazi. Obama hasn't been back to the region since 2009.

In Asia, however, Obama will be viewed as something of an elder statesman when he returns less than two weeks after winning re-election. The region is undergoing significant leadership changes, most notably in China, where the Communist Party tapped new leaders last week. Japan and South Korea will both hold new elections soon.

"Most of the leaders he'll meet with will not have a tenure as long as he will as president," said Michael Green, an Asia scholar at the Washington-based Center for Strategic and International Studies. "So he'll go into this in a very strong position."

The centerpiece of Obama's whirlwind Asia tour is his visit to Myanmar. It will be the first time a U.S. president has visited the former pariah state.

Myanmar has become something of a pet project for Obama and his national security aides, who have cheered the country's significant strides toward democracy. Obama lifted some U.S. penalties on Myanmar, appointed a permanent U.S. ambassador and hosted democracy leader Aung San Suu Kyi at the White House this year.

Many of the same strategic motivations behind Obama's larger focus on Asia are at play in Myanmar, which is known by the U.S. as Burma.

The country long has oriented itself toward China, but the easing of sanctions gives American businesses a chance to gain a foothold there. It's also an opportunity for the Obama administration to show other nations in the region, and elsewhere in the world, that there are benefits to aligning with the U.S.

Still, there's little denying that history has been a draw for Obama's team when it comes to its dealings with Myanmar. That's led to criticism from some human rights groups that say Obama's visit is premature given that the country continues to hold political prisoners and has been unable to stem some ethnic violence.

"This trip risks being an ill-timed presidential pat on the back for a regime that has looked the other way as violence rages, destroying villages and communities just in the last few weeks," said Suzanne Nossel, the U.S.-based director of Amnesty International.

But the White House believes that "if we want to promote human rights and promote American values, we intend to do so through engagement," Rhodes said Saturday as Obama flew to Asia.

He said it was important for Obama to convey the message about "the type of action we'd like to see locked in, in Burma as it relates to political reform, as it relates to economic reform, and national reconciliation."

Obama's other stops in the region also underscore the potential pitfalls of going all-in in Asia.

Thailand's 2006 coup, which led to the ouster of the prime minister, strained relations with the U.S. and raised questions in Washington about the stability of its longtime regional ally. Cambodia, where Obama's visit also marks the first by a U.S. president, has a dismal human rights record.

White House officials have emphasized that Obama is visiting Cambodia because it is hosting the East Asia Summit, an annual meeting the U.S. now attends. Aides say the president will voice his human rights concerns during his meeting with Hun Sen, Cambodia's long-serving prime minister.

Still, human rights groups fear Obama's visit will be seen within Cambodia as an affirmation of the prime minister and a sign to opposition groups that the U.S. stands with the government, not with them.

Secretary of State Hillary Rodham Clinton was also traveling to Thailand where she was going to join Obama. Clinton then was to fly to Myanmar with Obama on Air Force One. It will be the last joint trip for the president and his secretary of state, the once presidential rival who went on to become Obama's peripatetic chief diplomat. Clinton is planning on leaving the administration.

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Follow Julie Pace at http://twitter.com/jpaceDC

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Lady Gaga tweets some racy images before concert

BUENOS AIRES, Argentina (AP) — Lady Gaga's tweets were getting a lot of attention ahead of her Buenos Aires concert Friday night.

The Grammy-winning entertainer has more than 30 million followers on Twitter and that's where she shared a link this week to a short video showing her doing a striptease and fooling around in a bathtub with two other women.

She told her followers that it's a "surprise for you, almost ready for you to TASTE."

Then, in between concerts in Brazil and Argentina, she posted a picture Thursday on her Twitter page showing her wallowing in her underwear and impossibly high heels on top of the remains of what appears to be a strawberry shortcake.

"The real CAKE isn't HAVING what you want, it's DOING what you want," she tweeted.

Lady Gaga wore decidedly unglamorous baggy jeans and a blouse outside her Buenos Aires hotel Thursday as three burly bodyguards kept her fans at bay. Another pre-concert media event where she was supposed to be given "guest of honor" status by the city government Friday afternoon was cancelled.

After Argentina, she is scheduled to perform in Santiago, Chile; Lima, Peru; and Asuncion, Paraguay, before taking her "Born This Way Ball" tour to Africa, Europe and North America.

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Israel bombards Gaza Strip, shoots down rocket

GAZA CITY, Gaza Strip (AP) — Israel destroyed the headquarters of Hamas' prime minister and blasted a sprawling network of smuggling tunnels in the southern Gaza Strip on Saturday, broadening a blistering four-day-old offensive against the Islamic militant group even as diplomatic efforts to broker a cease-fire appeared to be gaining steam.

In neighboring Egypt, President Mohammed Morsi hosted leaders from Hamas and two key allies, Qatar and Turkey, to seek a way to end the fighting.

"There are discussions about the ways to bring a cease-fire soon, but there are no guarantees until now," Morsi said at a news conference. He said he was working with Turkey, Arab countries, the U.S., Russia and western European countries to halt the fighting.

Israel launched the operation on Wednesday in what it said was an effort to end months of rocket fire out of the Hamas-ruled territory. It began the offensive with an unexpected airstrike that killed Hamas' powerful military chief, and since then has relentlessly targeted suspected rocket launchers and storage sites.

In all, 46 Palestinians, including 15 civilians, have been killed and more than 400 civilians wounded, according to medical officials. Three Israeli civilians have been killed and more than 50 wounded.

Israeli military officials expressed satisfaction with their progress Saturday, claiming they have inflicted heavy damage to Hamas.

"Most of their capabilities have been destroyed," Maj. Gen. Tal Russo, Israel's southern commander, told reporters. Asked whether Israel is ready to send ground troops into Gaza, he said: "Absolutely."

The White House said President Barack Obama was also in touch with the Egyptian and Turkish leaders. The U.S. has solidly backed Israel so far.

Speaking on Air Force One, deputy national security adviser Ben Rhodes said that the White House believes Israel "has the right to defend itself" against attack and that the Israelis will make their own decisions about their "military tactics and operations."

The White House, which like Israel considers Hamas a terrorist organization, also continued to support Israel. "We believe Israel has a right to defend itself, and they'll make their own decisions about the tactics they use in that regard," deputy national security adviser Ben Rhodes told reporters on Air Force One.

Despite the bruising offensive, Israel has failed to slow the barrages of rockets from Gaza.

The Israeli military said 160 rockets were launched into Israel on Saturday, raising the total number to roughly 500 since this week's fighting began. Eight Israelis, including five civilians, were lightly wounded Saturday, the army said.

Israel carried out at least 300 airstrikes on Saturday, the military said, and it broadened its array of targets. One air raid flattened the three-story office building used by Hamas' prime minister, Ismail Haniyeh. He was not inside the building at the time.

In southern Gaza, aircraft went after the tunnels that militants use to smuggle in weapons and other contraband from neighboring Egypt. Tunnel operators said the intensity of the bombing was unprecedented, and that massive explosions could be heard kilometers (miles) away, both in Gaza and in Egypt.

The operators, speaking on condition of anonymity because of the illicit nature of their business, said they cannot approach the tunnel area to assess the damage, but the blasts appeared to be more powerful than in Israel's last major push to destroy the tunnels during a previous offensive four years ago. The tunnels are a key lifeline for Hamas, bringing in both weapons and supporting a lucrative trade that helps fund the group's activities.

Missiles also smashed into two small security facilities and the massive Hamas police headquarters in Gaza City, setting off a huge blaze that engulfed nearby houses and civilian cars parked outside, the Interior Ministry reported. No one was inside the buildings.

Air attacks knocked out five electricity transformers, cutting off power to more than 400,000 people in southern Gaza, according to the Gaza electricity distribution company. People switched on backup generators for limited electrical supplies.

Hamas has unveiled an arsenal of more powerful, longer-range rockets this week, and for the first time has struck at Israel's two largest cities, Jerusalem and Tel Aviv. Both cities, more than 70 kilometers (45 miles) from Gaza, had previously been beyond rocket range.

In a psychological boost for Israel, a new rocket-defense system known as "Iron Dome" knocked down a rocket headed toward Tel Aviv, eliciting cheers from relieved residents huddled in fear after air raid sirens sounded in the city.

Associated Press video showed a plume of smoke following an intercepting missile out of a rocket-defense battery deployed near the city, followed by a burst of light overhead as it struck its target.

Police said a second rocket also targeted Tel Aviv. It was not clear where it landed or whether it was shot down. No injuries were reported. It was the third straight day the city was targeted.

Israel says the Iron Dome system has shot down some 250 of 500 rockets fired toward the country this week, most in southern Israel near Gaza.

Saturday's interception was the first time Iron Dome has been deployed in Tel Aviv. The battery was a new upgraded version that was only activated on Saturday, two months ahead of schedule, the Defense Ministry said.

Israel has vowed to stage a ground invasion, a scenario that would bring the scale of fighting closer to that of a war four years ago. Hamas was badly bruised during that conflict but has since restocked its arsenal with more and better weapons. Five years after seizing control of Gaza, it has also come under pressure from smaller, more militant groups to prove its commitment to fighting Israel as it turns its focus to governing the seaside strip.

Israel's Defense Minister Ehud Barak has authorized the emergency call-up of up to 75,000 reserve troops ahead of a possible ground offensive. Israel has massed thousands of troops and dozens of tanks and armored vehicles along the border in recent days.

Egypt, which is led by Hamas' parent movement, the Muslim Brotherhood, has been spearheading efforts to forge a cease-fire. Morsi has vowed to stand strong with the people of Gaza and this week recalled Cairo's ambassador from Israel to protest the offensive.

Quietly, though, non-Muslim Brotherhood members in Morsi's government are said to be pushing Hamas to end its rocket fire on Israel. Morsi is under pressure not to go too far and risk straining ties with Israel's ally, the United States.

The Hamas website said Saturday that its leader, Khaled Meshaal, met with the head of Egyptian intelligence for two hours Saturday in Cairo, a day after the Egyptian official was in the Gaza Strip trying to work out an end to the escalation in violence.

Hamas has not immediately accepted Egypt's proposal for a cease-fire, but the group's website said it could end its rocket fire if Israel agrees to end "all acts of aggression and assassination" and lift its five-year Israeli blockade on Gaza. Egypt will present the Hamas position to Israeli officials.

Israeli officials say they are not interested in a "timeout," and want firm guarantees that the rocket fire, which has paralyzed life in an area home to 1 million Israelis, finally ends. Past cease-fires have been short lived.

Israeli Prime Minister Benjamin Netanyahu said he spoke with the leaders of Britain, Poland, Portugal, Bulgaria to press his case. "No government in the world would allow a situation where its population lives under the constant threat of rockets," Netanyahu told them, according to a statement from his office.

The diplomatic activity in Cairo illustrated Hamas' rising influence in a changing Middle East. The Arab Spring has brought Islamists to power and influence across the region, helping Hamas emerge from years of isolation.

Morsi warned that a ground operation by Irael will have "repercussions" across the region. "All must realize the situation is different than before, and the people of the region now are different than before and the leaders are different than before," he said at a joint press conference with Turkey's Islamist prime minister, Recep Tayyip Erdogan. Erdogan, like Morsi, leads an Islamist government that has chilly diplomatic ties with Israel.

On Friday, Morsi sent his prime minister to Gaza on a solidarity mission with Hamas. And on Saturday, Tunisia's Foreign Minister Rafik Abdessalem visited Gaza as well.

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Federman reported from Jerusalem. Associated Press writers Karin Laub in Gaza City and Aya Batrawy in Cairo contributed reporting.

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Pakistan releases son of Afghan militant leader

PESHAWAR, Pakistan (AP) — The son of a legendary Afghan mujahedeen leader was among a group of Taliban prisoners released by Pakistan to help jumpstart peace negotiations with the militant group, the man's cousin and a family friend said Friday.

The decision to release the prisoners is seen as a signal to neighboring Afghanistan that Pakistan might be willing to take concrete steps to revive efforts to lure the group to the negotiating table.

Pakistan released Anwarul Haq Mujahid on Thursday, and he joined his family in the northwestern Pakistani city of Peshawar, said the cousin and family friend, speaking on condition of anonymity because they were not authorized to talk to the media.

Mujahid is the son of the late Maulvi Mohammad Yunus Khalis who fought against the Soviets in Afghanistan in the 1980s. Khalis, who was once invited to the White House by former President Ronald Regan, died in 2006.

Afghan officials said Thursday that Pakistan freed eight Taliban prisoners and agreed to release many more. Mujahid was not among the eight listed by the Afghan officials, which means at least nine prisoners have been freed.

The most prominent prisoner freed was former Justice Minister Nooruddin Turabi who served when the Taliban ruled Afghanistan.

The U.S. and its allies fighting in Afghanistan are pushing to strike a peace deal with the Taliban so they can withdraw most of their troops by the end of 2014. The prisoner release could help, but considerable obstacles remain. It is unclear whether the Taliban even intend to take part in the process, rather than just wait until foreign forces withdraw.

Pakistan is seen as key to the peace process. Islamabad has ties to the Taliban that date back to the 1990s, and many of the group's leaders are believed to be based on Pakistani territory, having fled there following the U.S.-led invasion of Afghanistan in 2001.

Also Friday, a Pakistani lawyer accused the military of sending thugs to beat him up after he challenged the army chief in court.

Inam Ur Raheem, a retired military lawyer, said three vehicles surrounded his taxi Wednesday night in the garrison city of Rawalpindi. Several unidentified men jumped out and attacked him with sticks, leaving him with cuts and bruises. He claimed they said they were there to teach him a lesson.

The attack came a day after Raheem filed a petition in the Islamabad High Court challenging the validity of a three-year extension given to army chief Gen. Ashfaq Parvez Kayani in 2010.

The army denied any role in the attack Friday, calling Raheem's allegations baseless.

The New York Times first reported the attack Thursday.

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Associated Press writer Munir Ahmed contributed to this report from Islamabad.

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Pittsburgh airport to offer free ‘cell phone’ lot
















IMPERIAL, Pa. (AP) — Pittsburgh International Airport is offering free parking for folks who want to sit in their cars and wait for arriving passengers to call on cell phones to say they’ve arrived.


Allegheny County Airport Authority officials are hoping the plan will prevent motorists from congesting the curb near the airport’s terminal or the access roads around it by driving around in circles waiting for cell phone calls from arrivals.













Drivers can now park free for an hour in the extended term lot farthest from the terminal, and pay only $ 1 for a second hour of parking. After two hours, the spots will cost $ 8.


Gadgets News Headlines – Yahoo! News



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Pitbull, Ke$ha rehearse for American Music Awards

LOS ANGELES (AP) — Pitbull dressed up and Ke$ha went casual for American Music Awards rehearsals.

The entertainers popped by the Nokia Theatre Friday to practice the performances they've planned for Sunday's show.

Ke$ha was surrounded by male dancers as she bounced around the stage in sneakers, striped leggings and a torn black T-shirt. She played a giant golden drum, was carried aloft by her dancers and closed the rendition of her new hit "Die Young" by writhing on stage as fireworks rained down overhead.

Pitbull, fresh off his performance at Thursday's Latin Grammy Awards, arrived wearing crisp white pants, a red polo shirt and a tan blazer. After joking with his band in Spanish, he ditched the blazer and added shades to rehearse "Don't Stop the Party," for which he shares the stage with two drummers, two keyboardists, two ballerinas and a DJ.

Justin Bieber, Kelly Clarkson, Usher, Carrie Underwood, Taylor Swift, No Doubt, Christina Aguilera and Nicki Minaj are also set to perform during the three-hour ceremony, which will be broadcast live Sunday on ABC.

Stevie Wonder and Ryan Seacrest will also honor the late Dick Clark, who created the American Music Awards, at the 40th anniversary show.

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AP Entertainment Writer Sandy Cohen will be tweeting from the American Music Awards. Follow her at www.twitter.com/APSandy .

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Online:

http://beta.abc.go.com/shows/american-music-awards

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Israelis, Palestinians lob threats via Twitter

Poaching and trafficking -- a menace for already endangered animals http://t.co/IO6vY4uc
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PM to dissolve Japan's parliament, call elections

TOKYO (AP) — Prime Minister Yoshihiko Noda is poised to dissolve Japan's parliament, setting the stage for elections next month that will likely end the ruling Democrats' three years in power.

Polls suggest that the opposition Liberal Democratic Party, which led Japan for most of the post-World War II era, would win the most seats in the 480-seat lower house, but far short of a majority.

It is likely that no party will emerge as a clear winner in the lower house election and the party would have to form a coalition to govern. Reports say polls would be set for Dec. 16.

Noda abruptly said Wednesday he would dissolve parliament on Friday if the opposition would agree to key reforms, including shrinking the size of parliament.

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Andre 3000 isn't in a rush to record new album

NEW YORK (AP) — In order to capture his best version of Jimi Hendrix for an upcoming biopic, Andre 3000 said he had to think of him as a regular dude and not a rock star.

"I didn't look at him as an icon because when you're in it, you don't know you're an icon. You don't know you're an icon until another people say you're an icon," the 37-year-old said in an interview Tuesday.

"So I had to take it as a person, you know what I mean? And I just tried to say, 'Well, what would Jimi want people to know that they can't get off of YouTube?' And that's how I approached it," he said.

Hendrix died at age 27 in 1970. He was ranked No. 1 on Rolling Stone magazine's greatest guitarists of all-time list. His band, The Jimi Hendrix Experience, is known for iconic albums such as "Electric Ladyland" and "Are You Experienced."

"All Is by My Side," which focuses on the early days of Hendrix's career, will be released next year. Andre 3000 is excited to see the film, which he's finished shooting in Ireland. He believes the public "will be pleased."

Andre 3000, one-half of OutKast with Big Boi, has been out of the music scene in recent years, although he's been featured on songs by Beyonce, Frank Ocean, Rick Ross, Ke$ha and Young Jeezy.

OutKast's 2006 platinum-selling album, "Idlewild," which accompanied a film of the same name starring the duo, was their last album. Their 11-time platinum "Speakerboxxx/The Love Below" won the 2004 Grammy Award for album of the year.

Big Boi, who released a solo album two years ago to welcoming reviews, will release a new solo disc, "Vicious Lies and Dangerous Rumors," next month.

But Andre 3000 isn't in a rush to record an album.

"Some days I feel like I'll do it, some days I don't. Some days I feel like I don't need to, some days I feel like I want to do it before I die. So, I don't know where to fall. I am just hoping one day I get that inspiration," he said at an event for Gillette's eMO'gency Styler Tour, which supports men's health and prostate cancer programs. The tour kicked off in New York, with stops scheduled in Chicago and Houston.

"It's a feeling for me. Like, I can't just throw out an album to be rapping," he said. "And I don't even know if it will be rap. I don't even know what it will be."

However, he could find the inspiration and complete an album in just a few days: "It could be a rush situation. Like if I feel that feeling and I record an album in three days and I'm like, 'This is what I want to say right now' — that can happen, too."

He also says he's constantly writing songs.

"I write all the time. ... I actually stopped typing it in my phone because like a cloud is basically reading every thought that I have and I don't like that," he said. "So I went back to my paper and started writing."

He's not sure fans want a new OutKast album for the right reasons.

"Man, we've had a great ride. ... Like when we got into it when we were high school kids and we just wanted to do something fun and push it, and if it's not that then why do it?" he said.

"I'm not the type that prescribes to nostalgia, and most people say they want an OutKast album because they used to love it. Y'all don't even know if y'all still love it. You just know you used to love it. But you may not like it now, who knows?"

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Follow Mesfin Fekadu on Twitter at http://twitter.com/musicmesfin

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Diabetes rates rocket in Oklahoma, South

NEW YORK (AP) — The nation's diabetes problem is getting worse, and the biggest jump over 15 years was in Oklahoma, according to a new federal report issued Thursday.

The diabetes rate in Oklahoma more than tripled, and Kentucky, Georgia and Alabama also saw dramatic increases since 1995, the study showed.

The South's growing weight problem is the main explanation, said Linda Geiss, lead author of the report by the Centers for Disease Control and Prevention study.

"The rise in diabetes has really gone hand in hand with the rise in obesity," she said.

Bolstering the numbers is the fact that more people with diabetes are living longer because better treatments are available.

The disease exploded in the United States in the last 50 years, with the vast majority from obesity-related Type 2 diabetes. In 1958, fewer than 1 in 100 Americans had been diagnosed with diabetes. In 2010, it was about 1 in 14.

Most of the increase has happened since 1990.

Diabetes is a disease in which the body has trouble processing sugar; it's the nation's seventh leading cause of death. Complications include poor circulation, heart and kidney problems and nerve damage.

The new study is the CDC's first in more than a decade to look at how the nationwide boom has played out in different states.

It's based on telephone surveys of at least 1,000 adults in each state in 1995 and 2010. Participants were asked if a doctor had ever told them they have diabetes.

Not surprisingly, Mississippi — the state with the largest proportion of residents who are obese — has the highest diabetes rate. Nearly 12 percent of Mississippians say they have diabetes, compared to the national average of 7 percent.

But the most dramatic increases in diabetes occurred largely elsewhere in the South and in the Southwest, where rates tripled or more than doubled. Oklahoma's rate rose to about 10 percent, Kentucky went to more than 9 percent, Georgia to 10 percent and Alabama surpassed 11 percent.

An official with Oklahoma State Department of Health said the solution is healthier eating, more exercise and no smoking.

"And that's it in a nutshell," said Rita Reeves, diabetes prevention coordinator.

Several Northern states saw rates more than double, too, including Washington, Idaho, Montana, Wyoming, South Dakota, Minnesota, Missouri, Ohio and Maine.

The study was published in CDC's Morbidity and Mortality Weekly Report.

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Associated Press writer Ken Miller in Oklahoma City contributed to this report.

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Online:

CDC report: http://tinyurl.com/cdcdiabetesreport

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U.S. backs Israeli response to Gaza attacks

Israeli soldiers ride on top of an armored personnel carrier close to the Israel-Gaza border, in southern Israel. …The White House on Thursday threw its full support behind Israel's military response to a barrage of rockets fired by the Islamist Palestinian movement Hamas that rules the Gaza Strip. Deputy National Security Adviser for Strategic Communications Ben Rhodes said it would be "up to the Israeli government" whether to follow up punishing airstrikes with a ground assault.


"Our view is that the Israelis have the right of self-defense when their citizens are faced with the threat of indiscriminate rocket fire from within Gaza," Rhodes told reporters on a conference call.


Asked whether the Obama administration would have any issues with an Israeli ground assault, Rhodes replied that "ultimately, it's up to the Israeli government to make determinations about how they're going to carry out their military objectives."


The Associated Press has reported that Hamas fired more than 200 rockets on Thursday, killing three people, and that Israel seemed to be gearing up for a ground invasion of Gaza. The escalating conflict amounted to President Barack Obama's first major foreign policy test since winning re-election Nov. 6. Rhodes said American officials were in close consultation with their Israeli counterparts "to have an understanding of their plans going forward." The Obama administration has been in discussions with Turkey, Egypt and "some of our European partners," he said, thought to have sway over Hamas in order to get them to urge the militant organization to halt its rocket attacks.


"At the United Nations, where this is being discussed, we've sought to keep the focus where it should be—which is on Hamas's rocket fire as the precipitating cause here," Rhodes explained.


"What we've also said is that the best course of action would be for there to be a general de-escalation of the violence, but that the onus is on Hamas—and those with influence over Hamas—to help bring about that de-escalation, so that we don't see a widening conflict," he told reporters. "So we certainly want to see a de-escalation, we certainly want to see a broader conflict avoided."


The official noted that the White House has urged Israel to take "all steps ... to avoid civilian casualties." He added, "And we deeply regret the loss of life on the Israeli and Palestinian side."


Israeli Ambassador to the United States Michael Oren briefed key senators on the operation. The lawmakers—Democrats and Republicans—released a joint statement expressing "solidarity" with Israel while warning that "escalation will only lead to further suffering on both sides."


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Report: Sri Lankan war was grave failure for UN

UNITED NATIONS (AP) — A United Nations report released Wednesday said inadequate efforts by the world body to protect civilians during the bloody final months of Sri Lanka's civil war marked a "grave failure" that led to suffering for hundreds of thousands of people.

The report was unusually scathing for an official U.N. critique.

The report accused U.N. staff in Colombo of not perceiving that preventing civilian deaths was their responsibility and accused their bosses at U.N. headquarters of not telling them otherwise. A separate U.N. report released last year said up to 40,000 ethnic minority Tamil civilians may have been killed in the war's final months.

"This report is a benchmark moment for the U.N. in the same way that Rwanda was," said Gordon Weiss, a former U.N. spokesman in Sri Lanka.

The report accused U.N. officials and member states of being reluctant to interfere and leaving the conflict in a "vacuum of inaction."

"The report concludes that the United Nations system failed to meet its responsibilities — highlighting, in particular, the roles played by the Secretariat, the agencies and programs of the U.N. Country Team and the members of the Security Council and Human Rights Council," Secretary-General Ban Ki-moon said in a statement.

The report was compiled by a committee headed by former U.N. official Charles Petrie. It investigated U.N. actions as the quarter-century war between the government, dominated by the ethnic Sinhalese majority, and minority Tamil rebels ended in 2009 in a wave of violence.

The BBC first reported on a draft of the report Tuesday.

The draft, obtained by The Associated Press shortly before the final report was released, began with an "executive summary" that detailed the U.N. failure on the ground, saying that the political conditions after the Sept. 11, 2001, terror attacks in the U.S. made countries less likely to stop a government fighting against a group — the Tamil Tiger rebels — that many had branded a terrorist organization.

The executive summary was deleted from the official published version issued on Wednesday.

The draft report painted a picture of a U.N. operation reluctant to criticize the government or accuse it of killing civilians with artillery bombardments, out of concern the government would respond by limiting U.N. humanitarian access — even through U.N. aid workers were barred from the northern war zone in late 2008.

Top U.N. officials in the country repeatedly worked to soften statements to remove casualty figures and accusations of possible war crimes against the government, the official report said. When death tolls its staff was compiling were released, top officials dismissed them as unverified despite the rigorous methodology being used, the report said.

When U.N. satellite images confirmed heavy artillery shelling in the war zone and showed far more civilians there than the government claimed, the top U.N. official in Sri Lanka downplayed the evidence in a letter to the government, the final version of the report said. At the same time, member states did not hold a single formal meeting on the conflict in its final months in the Security Council, Human Rights Council or the General Assembly.

"The UN set itself up for failure, in Sri Lanka," the draft report said, in another quote deleted from the final, official report.

The report also accused the government of working to intimidate U.N. staff, of withholding visas of those critical of the government and of planting false allegations against them in the media.

The U.N. representative for Human Rights Watch, Philippe Bolopion, said "The U.N.'s dereliction of duty in Sri Lanka is a stark reminder of what happens when human rights concerns are marginalized or labeled as too political."

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Nessman reported from New Delhi.

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Shania Twain makes horseback arrival for Vegas gig

LAS VEGAS (AP) — Country music star Shania Twain arrived on horseback Wednesday for a two-year headline gig at Caesars Palace, parading up the Las Vegas Strip with a herd of 40 horses.

Promoters called the event a stampede, but hooves were kept to a steady, slow gait by nine wranglers who escorted Twain to a reception crowd of several hundred people in front of the famous Caesars fountains. Dozens more people watched from the sidewalk of the Flamingo resort across Las Vegas Boulevard.

"We could either lose a few hundred dollars inside or come out and see what kind of spectacle she puts on," said Steve Huffman, a UPS manager from Charleston, W.Va., who watched with his wife, Debi, from an overhead pedestrian walkway.

The couple was in town for his 52nd birthday and learned through a Twitter message that Twain planned to arrive on a horse. They identified Twain's hit, "Man, I Feel Like a Woman," as the country singer rode up the street, and they said they'll plan to see the show next year.

"Still The One" blasted on speakers as Twain stepped onto a temporary outdoor stage near fountains made famous by events including daredevil Evel Knievel's motorcycle crash during a stunt on New Year's Eve 1967.

To some, Twain's arrival echoed singer Frank Sinatra's heralded arrival on a camel at the old Dunes hotel in September 1955.

Twain's show titled "Shania: Still the One" opens Dec. 1 at the nearly 4,300-seat Colosseum at Caesars Palace. The venue also hosts entertainers Celine Dion, Elton John, Jerry Seinfeld and others.

Twain, 47, is touted as one of the best-selling female country artists of all time. The Canadian singer-songwriter has sold more than 75 million albums worldwide.

Las Vegas police, including several on horseback, diverted traffic on the busy casino corridor for about 30 minutes for the spectacle.

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New gene triples risk for Alzheimer's disease

Scientists have identified a new gene variant that seems to strongly raise the risk for Alzheimer's disease, giving a fresh target for research into treatments for the mind-robbing disorder.

The problem gene is not common — less than 1 percent of people are thought to have it — but it roughly triples the chances of developing Alzheimer's compared to people with the normal version of the gene. It also seems to harm memory and thinking in older people without dementia.

The main reason scientists are excited by the discovery is what this gene does, and how that might reveal what causes Alzheimer's and ways to prevent it. The gene helps the immune system control inflammation in the brain and clear junk such as the sticky deposits that are the hallmark of the disease. Mutations in the gene may impair these tasks, so treatments to restore the gene's function and quell inflammation may help.

"It points us to potential therapeutics in a more precise way than we've seen in the past," said Dr. William Thies, chief medical and scientific officer of the Alzheimer's Association, which had no role in the research. Years down the road, this discovery will likely be seen as very important, he predicted.

It is described in a study by an international group published online Wednesday by the New England Journal of Medicine.

About 35 million people worldwide have dementia, and Alzheimer's is the most common type. In the U.S., about 5 million have Alzheimer's. Medicines such as Aricept and Namenda just temporarily ease symptoms. There is no known cure.

Until now, only one gene — ApoE — has been found to have a big impact on Alzheimer's risk. About 17 percent of the population has at least one copy of the problem version of this gene but nearly half of all people with Alzheimer's do. Other genes that have been tied to the disease raise risk only a little, or cause the less common type of Alzheimer's that develops earlier in life, before age 60.

The new gene, TREM2, already has been tied to a couple other forms of dementia. Researchers led by deCODE Genetics Inc. of Iceland honed in on a version of it they identified through mapping the entire genetic code of more than 2,200 Icelanders.

Further tests on 3,550 Alzheimer's patients and more than 110,000 people without dementia in several countries, including the United States, found that the gene variant was more common in Alzheimer's patients.

"It's a very strong effect," raising the risk of Alzheimer's by three to four times — about the same amount as the problem version of the ApoE gene does, said Dr. Allan Levey, director of an Alzheimer's program at Emory University, one of the academic centers participating in the research.

Researchers also tested more than 1,200 people over age 85 who did not have Alzheimer's disease and found that those with the variant TREM2 gene had lower mental function scores than those without it. This adds evidence the gene variant is important in cognition, even short of causing Alzheimer's.

"It's another piece in the puzzle. It suggests the immune system is important in Alzheimer's disease," said Andrew Singleton, a geneticist with the National Institute on Aging, which helped pay for the study.

One prominent scientist not involved in the study — Dr. Rudolph Tanzi, a Harvard Medical School geneticist and director of an Alzheimer's research program at Massachusetts General Hospital — called the work exciting, but added a caveat.

"I would like to see more evidence that this is Alzheimer's" rather than one of the other dementias already tied to the gene, Tanzi said. Autopsy or brain imaging tests can show whether the cases attributed to the gene variant are truly Alzheimer's or misdiagnosed, he said.

___

Online:

Medical journal: http://www.nejm.org

Alzheimer's info: http://www.alzheimers.gov

Alzheimer's Association: http://www.alz.org

___

Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

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Clinton-Lewinsky 'spinners' resurface

WASHINGTON (Reuters) - It's a case of déjà vu in D.C.: some of the same high-profile, high-priced handlers who played supporting roles in the scandal over President Bill Clinton's affair with intern Monica Lewinsky have re-emerged in the sex scandal that has toppled one U.S. national security chief and threatens another.


It is unclear what will be the roles of the expensive legal and crisis-management talent drawn into the uproar over the relationships between former CIA director David Petraeus and Marine General John Allen and two female acquaintances. Neither Republicans nor Democrats in Congress appear to have an appetite for another year-long Monica-style media spectacle.


The latest scandal began with an FBI investigation into cyber-harassment, and indications so far are that ultimately the inquiry will produce no criminal charges.


Nonetheless, both women at the center of attention - Petraeus biographer and former mistress Paula Broadwell and Tampa socialite Jill Kelley, the woman to whom Broadwell is alleged to have sent suspected harassing emails - have turned for advice to veteran Washington lawyers and spin doctors with connections to the Lewinsky brouhaha.


On Monday, a source close to the Kelley family said that two Washington-based players in the Lewinsky scandal, trial lawyer Abbe Lowell and public relations adviser Judy Smith, were working for Kelley.


A day later, a Washington law firm which represented Lewinsky herself confirmed that one of its partners, Robert F. Muse, was representing Broadwell. The three advisors either were unavailable for comment or declined to comment.


It is not known whether Petraeus or Allen, who is the top U.S. military commander in Afghanistan, have retained attorneys.

 

A complaint by Kelley to the FBI about the harassing emails sparked an investigation that implicated Petraeus in a career-ending affair with Broadwell.


It also embroiled Kelley herself in the uproar over her still-murky relationship with Allen.


Kelley's lawyer, Lowell, who an insider said she had known for years, served as pro-Clinton Democratic Party chief counsel on a House impeachment inquiry. Recently he won a partial acquittal and partial mistrial for John Edwards, a former Democratic U.S. senator and vice presidential candidate who had been indicted for misusing undeclared campaign funds to support his mistress.


During the Clinton sex scandal, Smith, a one-time press aide to President George H.W. Bush, served as Lewinsky's spokeswoman. Smith also represented NFL quarterback Michael Vick, who was charged and convicted in a dogfighting cruelty case.


Smith also is a model for the main character in the ABC-TV drama "Scandal," a prime-time series in which ace spin-doctor Olivia Pope, along with a team of spies and ex-convicts, not only manages to sort out or cover up sex and spy scandals but also carries on a secret affair with a fictional U.S. president.


Muse's senior partner, Jacob Stein, and another prominent criminal lawyer from a different firm, Plato Cacheris, represented Lewinsky personally in a criminal investigation of Clinton by special prosecutor Kenneth Starr and a congressional inquiry which led to Clinton's impeachment by the House of Representatives but subsequent acquittal by the Senate. Muse himself did not represent Lewinsky, according to Cacheris.


Starr and a substantial special prosecution team pursued Clinton during the Lewinsky scandal. Starr turned his evidence over to the Republican-controlled House, which in a nationally televised broadcast impeached Clinton for high crimes and misdemeanors.


But Republicans could not muster the two-thirds majority in the Senate needed to remove Clinton from office. Republicans later were punished at the polls for what many of them conceded was a perceived overzealousness in pursuing Clinton.


CONGRESS WARY OF SPECTACLE


Lewinsky's lawyers were critical in helping her negotiate a legal thicket that included dealing with Starr's criminal investigators and the impeachment inquiry launched by Congress; she testified in both investigations. Lewinsky was also besieged for months by the media; eventually her team arranged decorous interviews with U.S. and British television networks.


Mindful of how the Lewinsky scandal played out, officials familiar with the views of both senior Democrats and Republicans in Congress say that congressional leaders are keen to avoid turning the scandal into a public extravaganza, even though there remain many unanswered questions.


If there are no public congressional hearings or a criminal prosecution, it is unclear what Broadwell's and Kelley's legal and public relations teams would do, apart from trying to manage news coverage and the hordes of paparazzi and TV cameramen now outside their clients' homes.


Lewinsky's lawyer, Cacheris, told Reuters that from what he could see, at this point Broadwell and Kelley do not know if there will be any charges against them. "These people are getting lawyers to ensure there is no criminal case," he added.


But Eric Dezenhall, a Washington crisis management expert, said some clients did not understand that there was a limit to how much even the most skilled lawyer and public relations specialist could do.


"You have to be very selective in the cases you take because you're going to end up with some very disgruntled clients," Dezenhall said.


(Editing by Warren Strobel and Paul Simao)

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The curse of commanding the Afghan war

A look at what went wrong for the four U.S. generals who have led U.S. and NATO forces in Afghanistan since 2008:

Gen. David McKiernan, June 2008 to June 2009

-Defense Secretary Robert Gates asked for McKiernan's resignation a year before his term as commander was set to end. The firing was seen as a rejection by newly elected President Barack Obama of McKiernan's conventional warfare approach in favor of the more targeted "counterinsurgency" strategy of working to undermine insurgents' pull on the population.

Gen. Stanley A. McChrystal, June 2009 to June 2010

-McChrystal, who had a background in special operations, came in with a mandate to remake the war effort with the help of "surge" troops ordered by Obama. A year into that push, an article in Rolling Stone magazine quoted members of McChrystal's team making disparaging comments about their commander in chief and other senior administration officials. Obama called McChrystal back to Washington to explain and forced him to resign.

Gen. David Petraeus, July 2010 to July 2011

-Petraeus took over the Afghan command to fill the void left by McChrystal's abrupt departure and agreed to serve for one year. He completed that term and then retired from the military to become CIA director in September 2011. Petraeus resigned as CIA director on Nov. 9 after he had an extramarital affair with his biographer. The affair came out as part of an FBI investigation into suspicious emails between the biographer and another woman.

Gen. John Allen, July 2011 to present

-Allen was appointed by Obama to oversee the drawdown of U.S. and international forces ahead of the planned transfer of security responsibility to the Afghan government in 2014. Pentagon officials said early Tuesday that Allen is under investigation for thousands of alleged "inappropriate communications" with the second woman involved in the Petraeus case, a Florida socialite. Allen's nomination to become the next commander of U.S. European Command and the commander of NATO forces in Europe has now been put on hold.

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RIM sees BB10 devices in stores soon after launch
















WATERLOO, Ontario (Reuters) – Research In Motion is confident its new BlackBerry 10 devices will be 100 percent ready for the January 30 launch and available in stores “not too long after” that, Chief Operating Officer Kristian Tear said on Tuesday.


“We’re working hard right now to make sure all the bits and pieces and all the details are in place for the date, when the devices will be available for consumers and enterprises,” Tear told Reuters in an interview.













RIM, which virtually invented the concept of mobile email with its first line of BlackBerry devices more than a decade ago, was roundly criticized for the botched 2011 launch of its PlayBook tablet computer, which RIM had hoped would compete with Apple’s blockbuster iPad.


The PlayBook looked pretty and had top-of-the-line hardware. But its software was far from complete at the launch and needed multiple updates.


The device also lacked the library of apps available on the iPad and on devices that run on Google Inc’s competing Android operating system.


RIM says its the new devices will be faster and smoother than its existing phones and have a large catalog of applications that are crucial to the success of any smartphone.


The company hopes the new devices will allow it to claw back some of the market share it has lost to Android and Apple phones.


Tear said RIM has used input from current BlackBerry users to influence the design of the new devices, The new phones both build on the strengths of RIM’s existing operating system and improve on its weak points, he said.


RIM last month began carrier testing on the new devices, with an initial rollout to more than 50 carriers. Tear, who joined RIM a few months ago from Sony Mobile Communications, said RIM was expanding that to a wider group of carriers across the globe.


“We submitted to 50 carriers to begin with, and obviously that number is increasing as we move forward,” he said. “Our ambition is to make this a global launch, everything will not happen at the same time, but it will be a global launch.”


RIM has said it initially plans to roll out a high-end touchscreen version of the device. Phones with the mini QWERTY keyboards that many long-time BlackBerry users adore will come a few weeks later, while lower-end versions of both devices will be launched later in the year.


The company has yet to say exactly when the devices will be available in stores worldwide or how much they will cost.


“We have to agree with carriers as well on what they want to announce when, so it’s not absolutely to our own discretion,” Tear said.


COST CUTTING


RIM, whose share price has fallen more than 90 percent from a 2008 peak around $ 148, is part way through a major restructuring, as it seeks to trim costs in the run-up to the launch of the new devices.


The company, which has also said it is examining its strategic options, is lowering operating costs by about $ 1 billion and cutting about 5,000 jobs, or about 30 percent of its workforce, by the time its fiscal year ends in early March.


“We are on track to deliver on that,” said Tear. “It is an ongoing process, when it comes to efficiencies and costs.”


RIM’s Chief Legal Officer Steve Zipperstein said the company is pushing ahead with its strategic review.


“The process is ongoing and it continues to be a focus on RIM’s senior management, but we have nothing to report at this moment,” said Zipperstein.


RIM shares, which have risen slightly over the last couple of months in the run-up to the launch of BB10 devices, closed 4.7 percent lower at $ 8.40 on Nasdaq. RIM’s Toronto-listed shares fell by a similar margin to C$ 8.40.


(Reporting by Euan Rocha; Editing by Janet Guttsman, Leslie Adler and Tim Dobbyn)


Gadgets News Headlines – Yahoo! News



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Man who accused Elmo puppeteer of teen sex recants

NEW YORK (AP) — A man who accused Elmo puppeteer Kevin Clash of having sex with him when he was a teenage boy has recanted his story.

In a quick turnabout, the man on Tuesday described his sexual relationship with Clash as adult and consensual.

Clash responded with a statement of his own, saying he is "relieved that this painful allegation has been put to rest." He had no further comment.

The man, who has not identified himself, released his statement through the Harrisburg, Pa., law firm Andreozzi & Associates.

Sesame Workshop, which produces "Sesame Street" in New York, soon followed by saying, "We are happy that Kevin can move on from this unfortunate episode."

The whirlwind episode began Monday morning, when Sesame Workshop startled the world by announcing that Clash had taken a leave of absence from "Sesame Street" in the wake of allegations that he had had a relationship with a 16-year-old.

Clash, a 52-year-old divorced father of a grown daughter, swiftly denied the charges of his accuser, who is in his early 20s. In that statement Clash acknowledged that he is gay but said the relationship had been between two consenting adults.

Though it remained unclear where the relationship took place, sex with a person under 17 is a felony in New York if the perpetrator is at least 21.

Sesame Workshop, which said it was first contacted by the accuser in June, had launched an investigation that included meeting with the accuser twice and meeting with Clash. Its investigation found the charge of underage conduct to be unsubstantiated.

Clash said on Monday he would take a break from Sesame Workshop "to deal with this false and defamatory allegation."

Neither Clash nor Sesame Workshop indicated on Tuesday when he might return to the show, on which he has performed as Elmo since 1984.

Elmo had previously been a marginal character, but Clash, supplying the fuzzy red puppet with a high-pitched voice and a carefree, child-like personality, launched the character into major stardom. Elmo soon rivaled Big Bird as the face of "Sesame Street."

Though usually behind the scenes, Clash meanwhile achieved his own measure of fame. In 2006, he published an autobiography, "My Life as a Furry Red Monster," and he was the subject of the 2011 documentary "Being Elmo: A Puppeteer's Journey."

He has won 23 daytime Emmy awards and one prime-time Emmy.

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Online:

http://www.sesamestreet.org

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Report: FDA wanted to close Mass pharmacy in 2003

WASHINGTON (AP) — Nearly a decade ago, federal health inspectors wanted to shut down the pharmacy linked to a recent deadly meningitis outbreak until it cleaned up its operations, according to congressional investigators.

About 440 people have been sickened by contaminated steroid shots distributed by New England Compounding Center, and more than 32 deaths have been reported since the outbreak began in September, according to the Centers for Disease Control and Prevention. That has put the Framingham, Mass.-based pharmacy at the center of congressional scrutiny and calls for greater regulation of compounding pharmacies, which make individualized medications for patients and have long operated in a legal gray area between state and federal laws.

The House Energy and Commerce Committee released a detailed history of NECC's regulatory troubles on Monday, ahead of a meeting Wednesday meeting to examine how the outbreak could have been prevented. The 25-page report summarizes and quotes from FDA and state inspection memos, though the committee declined to release the original documents.

The report shows that after several problematic incidents, Food and Drug Administration officials in 2003 suggested that the compounding pharmacy be "prohibited from manufacturing" until it improved its operations. But FDA regulators deferred to their counterparts in Massachusetts, who ultimately reached an agreement with the pharmacy to settle concerns about the quality of its prescription injections.

The congressional report also shows that in 2003 the FDA considered the company a pharmacy. That's significant because in recent weeks public health officials have charged that NECC was operating more as a manufacturer than a pharmacy, shipping thousands of doses of drugs to all 50 states instead of small batches of drugs to individual patients. Manufacturers are regulated by the FDA and are subject to stricter quality standards than pharmacies.

The report offers the most detailed account yet of the numerous regulatory complaints against the pharmacy, which nearly date back to its founding in 1998. Less than a year later, the company was cited by the state pharmacy board for providing doctors with blank prescription pads with NECC's information. Such promotional items are illegal in Massachusetts and the pharmacy's owner and director, Barry Cadden, received an informal reprimand, according to documents summarized by the committee.

Cadden was subject to several other complaints involving unprofessional conduct in coming years, but first came to the FDA's attention in 2002. Here are some key events from the report highlighting the company's early troubles with state and federal authorities:

__ In March of 2002 the FDA began investigating reports that five patients had become dizzy and short of breath after receiving NECC's compounded betamethasone repository injection, a steroid used to treat joint pain and arthritis that's different from the one linked to the current meningitis outbreak.

FDA inspectors visited NECC on April 9 and said Cadden was initially cooperative in turning over records about production of the drug. But during a second day of inspections, Cadden told officials "that he was no longer willing to provide us with any additional records," according to an FDA report cited by congressional investigators. The inspectors ultimately issued a report citing NECC for poor sterility and record-keeping practices but said that "this FDA investigation could not proceed to any definitive resolution," because of "problems/barriers that were encountered throughout the inspection."

__ In October of 2002, the FDA received new reports that two patients at a Rochester, N.Y., hospital came down with symptoms of bacterial meningitis after receiving a different NECC injection. The steroid, methylprednisolone acetate, is the same injectable linked to the current outbreak and is typically is used to treat back pain. Both patients were treated with antibiotics and eventually recovered, according to FDA documents cited by the committee.

When officials from the FDA and Massachusetts Board of Pharmacy visited NECC later in the month, Cadden said vials of the steroid returned by the hospital had tested negative for bacterial contamination. But when FDA scientists tested samples of the drug collected in New York they found bacterial contamination in four out of 14 vials sampled. It is not entirely clear whether FDA tested the same lot shipped to the Rochester hospital.

__ At a February 2003 meeting between state and federal officials, FDA staff emphasized "the potential for serious public consequences if NECC's compounding practices, in particular those relating to sterile products, are not improved." The agency issued a list of problems uncovered in its inspection to NECC, including a failure to verify if sterile drugs met safety standards.

But the agency decided to let Massachusetts officials take the lead in regulating the company, since pharmacies are typically regulated at the state level. It was decided that "the state would be in a better position to gain compliance or take regulatory action against NECC as necessary," according to a summary of the meeting quoted by investigators.

The FDA recommended the state subject NECC to a consent agreement, which would require the company to pass certain quality tests to continue operating. But congressional investigators say Massachusetts Board of Pharmacy did not take any action until "well over a year later."

__ In October 2004, the board sent a proposed consent agreement to Cadden, which would have included a formal reprimand and a three-year probationary period for the company's registration. The case ended without disciplinary action in 2006, when NECC agreed to a less severe consent decree with the state.

Massachusetts officials indicated Tuesday they are still investigating why NECC escaped the more severe penalty.

"I will not be satisfied until we know the full story behind this decision," the state's interim health commissioner Lauren Smith said in a transcript of her prepared testimony released a day ahead of delivery. Smith is one of several witnesses scheduled to testify Wednesday, including FDA Commissioner Margaret Hamburg.

The committee will also hear from the widow of 78-year-old Eddie C. Lovelace, a longtime circuit court judge in southern Kentucky. Autopsy results confirmed Lovelace received fungus-contaminated steroid injections that led to his death Sept. 17.

Joyce Lovelace will urge lawmakers to work together on legislation to stop future outbreaks caused by compounded drugs, according to a draft of her testimony.

"We now know that New England Compounding Pharmacy, Inc. killed Eddie. I have lost my soulmate and life's partner with whom I worked side by side, day after day for more than fifty years," Lovelace states.

Barry Cadden is also scheduled to appear at the hearing, after lawmakers issued a subpoena to compel him to attend.

The NECC has been closed since early last month, and Massachusetts officials have taken steps to permanently revoke its license. The pharmacy has recalled all the products it makes, including 17,700 single-dose vials of a steroid that tested positive for the fungus tied to the outbreak.

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Congress' choice whether Petraeus testifies on Benghazi attack

Holly Petraeus and Gen. David Petraeus walk past a seated Paula Broadwell (rear right) at his confirmation hearing …The White House said Tuesday that it was "up to Congress" whether to call former CIA Director David Petraeus to testify about the Sept. 11 attack in Benghazi, Libya.


"Congress [makes] decisions about who is called to testify," press secretary Jay Carney told reporters at his daily briefing.


The Intelligence Committees of the Senate and House of Representatives had been set to hear from Petraeus about the attack on the American compound in separate closed-door hearings on Thursday. But aides to both panels indicated that the retired Army general would be replaced by Mike Morrell, the acting CIA director.


"The president is confident that Acting Director Morrell is fully informed and capable of representing the CIA in a hearing about the incidents in Benghazi," Carney said.


Still, key senators have made it clear that Petraeus, whose shocking resignation came after the public disclosure of an extramarital affair, will ultimately need to be heard. The attack claimed the lives of U.S. Ambassador Chris Stevens and three other Americans.


Senate Intelligence Committee Chairwoman Dianne Feinstein, a Democrat, told MSNBC on Monday that her panel "should go ahead with Mike Morell and the way it is now set up."


"But I also think that the community should know that this is not sufficient," she continued. "And I have no doubt now that we will need to talk with David Petraeus. And we will likely do that in closed session, but it will be done one way or the other."

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Man charged with planning Prince Charles assault

AUCKLAND, New Zealand (AP) — Police say they caught a New Zealand man before he had a chance to throw a bucket of horse manure over Prince Charles and his wife Camilla during a royal visit to the Pacific nation.

Castislav "Sam" Bacanov, 76, pleaded not guilty in an Auckland court Tuesday to planning a crime in a public place. He has agreed under his bail conditions to keep at least 500 meters (1,600 feet) from the royal couple.

The Prince of Wales and the Duchess of Cornwall are on a six-day tour of New Zealand, the last leg of their Pacific tour marking Queen Elizabeth II's 60th Jubilee.

Police spokeswoman Noreen Hegarty said officers arrested Bacanov, a known anti-royalist, on Monday near a downtown Auckland venue where Charles and Camilla were due to appear. She said the royal couple had not yet arrived at the outdoor venue and were never in any danger.

Hegarty said officers were making sure the area was safe when they noticed the man with the bucket.

Bacanov is due to appear in court again on Nov. 27.

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'Skyfall' brings record Bond debut of $88.4M

LOS ANGELES (AP) — James Bond is cashing in at the box office.

"Skyfall," the 23rd film featuring the British super-spy, pulled in a franchise-record $88.4 million in its U.S. debut, bringing its worldwide total to more than $500 million since it began rolling out overseas in late October.

The top 20 movies at U.S. and Canadian theaters Friday through Sunday, followed by distribution studio, gross, number of theater locations, average receipts per location, total gross and number of weeks in release, as compiled Monday by Hollywood.com are:

1. "Skyfall," Sony, $88,364,714, 3,505 locations, $25,211 average, $90,564,714, one week.

2. "Wreck-It Ralph," Disney, $33,012,796, 3,752 locations, $8,799 average, $93,647,405, two weeks.

3. "Flight," Paramount, $14,785,097, 2,047 locations, $7,223 average, $47,455,396, two weeks.

4. "Argo," Warner Bros., $6,617,229, 2,763 locations, $2,395 average, $85,583,187, five weeks.

5. "Taken 2," Fox, $4,012,829, 2,487 locations, $1,614 average, $131,300,000, six weeks.

6. "Cloud Atlas," Warner Bros., $2,658,250, 2,023 locations, $1,314 average, $22,844,956, three weeks.

7. "The Man With the Iron Fists," Universal, $2,592,705, 1,872 locations, $1,385 average, $12,821,030, two weeks.

8. "Pitch Perfect," Universal, $2,573,350, 1,391 locations, $1,850 average, $59,099,993, seven weeks.

9. "Here Comes the Boom," Sony, $2,522,790, 2,044 locations, $1,234 average, $39,033,885, five weeks.

10. "Hotel Transylvania," Sony, $2,400,226, 2,566 locations, $935 average, $140,954,208, seven weeks.

11. "Paranormal Activity 4," Paramount, $1,980,033, 2,348 locations, $843 average, $52,600,612, four weeks.

12. "Sinister," Summit, $1,524,448, 1,554 locations, $981 average, $46,578,686, five weeks.

13. "Silent Hill: Revelation," Open Road Films, $1,300,137, 1,902 locations, $684 average, $16,383,406, three weeks.

14. "The Perks of Being a Wallflower," Summit, $1,132,924, 607 locations, $1,866 average, $14,614,770, eight weeks.

15. "Lincoln," Disney, $944,308, 11 locations, $85,846 average, $944,308, one week.

16. "Alex Cross," Summit, $911,973, 1,090 locations, $837 average, $24,603,042, four weeks.

17. "Fun Size," Paramount, $757,223, 1,301 locations, $582 average, $8,800,336, three weeks.

18. "Looper," Sony, $582,150, 491 locations, $1,186 average, $64,669,383, seven weeks.

19. "The Sessions," Fox, $545,550, 128 locations, $4,262 average, $1,655,222, four weeks.

20. "Seven Psychopaths," CBS Films, $404,812, 356 locations, $1,137 average, $14,098,469, five weeks.

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Universal and Focus are owned by NBC Universal, a unit of Comcast Corp.; Sony, Columbia, Sony Screen Gems and Sony Pictures Classics are units of Sony Corp.; Paramount is owned by Viacom Inc.; Disney, Pixar and Marvel are owned by The Walt Disney Co.; Miramax is owned by Filmyard Holdings LLC; 20th Century Fox and Fox Searchlight are owned by News Corp.; Warner Bros. and New Line are units of Time Warner Inc.; MGM is owned by a group of former creditors including Highland Capital, Anchorage Advisors and Carl Icahn; Lionsgate is owned by Lions Gate Entertainment Corp.; IFC is owned by AMC Networks Inc.; Rogue is owned by Relativity Media LLC.

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Online:

http://www.hollywood.com

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British medical journal slams Roche on Tamiflu

LONDON (AP) — A leading British medical journal is asking the drug maker Roche to release all its data on Tamiflu, claiming there is no evidence the drug can actually stop the flu.

The drug has been stockpiled by dozens of governments worldwide in case of a global flu outbreak and was widely used during the 2009 swine flu pandemic.

On Monday, one of the researchers linked to the BMJ journal called for European governments to sue Roche.

"I suggest we boycott Roche's products until they publish missing Tamiflu data," wrote Peter Gotzsche, leader of the Nordic Cochrane Centre in Copenhagen. He said governments should take legal action against Roche to get the money back that was "needlessly" spent on stockpiling Tamiflu.

Last year, Tamiflu was included in a list of "essential medicines" by the World Health Organization, a list that often prompts governments or donor agencies to buy the drug.

Tamiflu is used to treat both seasonal flu and new flu viruses like bird flu or swine flu. WHO spokesman Gregory Hartl said the agency had enough proof to warrant its use for unusual influenza viruses, like bird flu.

"We do have substantive evidence it can stop or hinder progression to severe disease like pneumonia," he said.

In the U.S., the Centers for Disease Control and Prevention recommends Tamiflu as one of two medications for treating regular flu. The other is GlaxoSmithKline's Relenza. The CDC says such antivirals can shorten the duration of symptoms and reduce the risk of complications and hospitalization.

In 2009, the BMJ and researchers at the Nordic Cochrane Centre asked Roche to make all its Tamiflu data available. At the time, Cochrane Centre scientists were commissioned by Britain to evaluate flu drugs. They found no proof that Tamiflu reduced the number of complications in people with influenza.

"Despite a public promise to release (internal company reports) for each (Tamiflu) trial...Roche has stonewalled," BMJ editor Fiona Godlee wrote in an editorial last month.

In a statement, Roche said it had complied with all legal requirements on publishing data and provided Gotzsche and his colleagues with 3,200 pages of information to answer their questions.

"Roche has made full clinical study data ... available to national health authorities according to their various requirements, so they can conduct their own analyses," the company said.

Roche says it doesn't usually release patient-level data available due to legal or confidentiality constraints. It said it did not provide the requested data to the scientists because they refused to sign a confidentiality agreement.

Roche is also being investigated by the European Medicines Agency for not properly reporting side effects, including possible deaths, for 19 drugs including Tamiflu that were used in about 80,000 patients in the U.S.

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Online:

www.bmj.com.tamiflu/

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Did Petraeus' mistress leak classified info?

Former CIA Director David Petraeus and author Paula Broadwell pose for a photo. (AP)A recent University of Denver address by Paula Broadwell has set off a torrent of speculation as to whether her affair with Gen. David Petraeus resulted in a leak of classified national security information.


New York magazine got things started by posting a video of Broadwell, author of Petraeus' biography, "All In," discussing details of the Sept. 11 attack on the American Consulate in Benghazi, Libya, at the Oct. 26 talk.


In the video, since posted by several sources to YouTube, Broadwell states: "Now, I don't know if a lot of you heard this, but the CIA annex had actually, had taken a couple of Libyan militia members prisoner, and they think that the attack on the consulate was an effort to try to get these prisoners back. So that's still being vetted."


That clip has led some to speculate whether Broadwell was exposing previously unreported details about the attack.


Other major media outlets, including CBS News and The Daily Beast, have picked up on the video clip. Wired goes a step further, stating as fact that Broadwell did reveal new information, writing: "It was a surprising disclosure, given the deep classification of the CIA's detention policies—and the enormous political stakes surrounding the Benghazi assault. But in many ways, it was only natural for Broadwell, given her evolution from Petraeus protegee to biographer to paramour and unofficial spokesperson."


And Politico points to a July panel discussion at the Aspen Security Forum during which Broadwell claims to have had access to classified information and to have attended high-level security meetings with Petraeus.


However, Broadwell's sound bite could be entirely innocuous, New York magazine notes: "It's also possible that she just misunderstood something she heard on Fox News."


The Fox News Channel reference concerns a report FNC reporter Jennifer Griffin made earlier the same day as Broadwell's university address, in which Griffin cited sources claiming that the CIA was holding high-value detainees in the Benghazi facility at the time of the attack.


You can watch an excerpt from Broadwell's University of Denver address below:



Griffin has since updated her reporting, noting that a well-placed Washington source confirms that Libyan militiamen were being held at the CIA annex and may have been a possible reason for the attack. Multiple intelligence sources, she also reported, said "there were more than just Libyan militia members who were held and interrogated by CIA contractors at the CIA annex in the days prior to the attack. Other prisoners from additional countries in Africa and the Middle East were brought to this location."


The CIA has denied keeping militants at the facility. CIA spokesman Preston Golson said, "Any suggestion that the agency is still in the detention business is uninformed and baseless."


Basically, so far we have a lot of speculation, with individuals commenting on a potential national security leak concerning details of a situation the government says never took place. Stay tuned.

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Man in Afghan uniform kills British soldier

KABUL, Afghanistan (AP) — A gunman wearing an Afghan army uniform shot and killed a member of the U.S.-led coalition forces fighting in Afghanistan on Sunday -- the latest in a spate of insider attacks that are fracturing the trust between NATO and Afghan forces.

Separately, officials said 11 Afghan civilians were killed by land mines on Sunday in explosions in the east and south.

The U.K. Ministry of Defense confirmed that the insider attack had claimed the life of a British soldier from The Royal Scots Borderers, 1st Battalion The Royal Regiment of Scotland. It said the soldier was shot by an individual wearing an Afghan army uniform at his base in the Nade-e Ali district of Helmand province.

The defense ministry did not name the serviceman but said his next of kin have been informed.

Mohammad Zarak, spokesman for the governor of southern Afghanistan's Helmand province, said the shooting took place in Nad Ali district after an argument between an Afghan soldier and coalition service members.

Coalition figures show at least 60 coalition service members have been killed so far this year and others have been wounded in about 45 insider attacks, where members of the Afghan security forces or insurgents dressed in their uniforms turn their guns on U.S. and allied troops.

The insider attacks have raised questions about how effectively the allied forces can train the Afghans to take over security of their own country in 2014 and beyond. Foreign forces are due to turn over security responsibility to the local military by the end of 2014.

A roadside bomb killed three men, two women and a baby in Khost province of eastern Afghanistan, deputy provincial police chief Youqib Khan said. He said their vehicle hit the bomb as they were returning from a hospital.

Three other civilians were killed when their vehicle detonated a land mine on the road between Helmand and Kandahar provinces, a government statement said.

Also in the south, two civilians who were walking were killed by a land mine in Khakrez district of Kandahar province, said Ahmad Jawed Faisal, a spokesman for the provincial governor.

The United Nations says homemade bombs continue to be the weapons that kill the most civilians in the war.

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Associated Press Writers Rahim Faiez, Mirwais Khan and Cassandra Vinograd contributed to this report.

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Bond soars with record $87.8M 'Skyfall' debut

LOS ANGELES (AP) — James Bond's "Skyfall" has extended its worldwide box-office rule to North America, hauling in a franchise-record $87.8 million in its first weekend at U.S. theaters.

Adding in $2.2 million from Thursday night previews at IMAX and other large-format theaters, "Skyfall" has taken in $90 million domestically, according to studio estimates Sunday.

That lifts the worldwide total for "Skyfall" to $518.6 million since it began rolling out overseas in late October. Internationally, the 23rd Bond flick added $89 million this weekend to raise its overseas revenue to $428.6 million.

The third installment starring Daniel Craig as British super-spy Bond, "Skyfall" outdid the $67.5 million U.S. debut of 2008's "Quantum of Solace," the franchise's previous best opening. "Skyfall" more than doubled the $40.8 million debut of Craig's first Bond film, 2006's "Casino Royale."

"Skyfall" already has passed the $407.7 million overseas total for "Quantum of Solace" and by Monday, it will top the $432.2 million international haul for "Casino Royale."

The Craig era has reinvigorated one of Hollywood's most-enduring franchises, whose first big-screen Bond adventure, "Dr. No," debuted 50 years ago.

"It's quite a testament to Bond, considering it's the 50th anniversary. What a great anniversary present," said Rory Bruer, head of distribution at Sony, which produces the Bond films along with MGM.

"Skyfall" was the weekend's only new wide release, but Steven Spielberg's "Lincoln" had a huge start in a handful of theaters. Starring Daniel Day-Lewis as the 16th president, "Lincoln" took in $900,000 in 11 theaters for a whopping average of $81,818 a cinema. By comparison, "Skyfall" averaged $25,050 in 3,505 theaters.

"Lincoln" centers on the months leading up to the president's assassination in April 1865, as he maneuvers to pass the 13th amendment abolishing slavery and end the Civil War. Distributor Disney will expand "Lincoln" into nationwide release of about 1,600 theaters Friday and may widen the film further over Thanksgiving week.

The film has strong Academy Awards prospects for two-time directing winner Spielberg, two-time acting recipient Day-Lewis and the rest of the cast, which includes Oscar winners Sally Field and Tommy Lee Jones.

"The performances are some of the greatest of recent time," said Dave Hollis, head of distribution for Disney. "I don't know if you're ever going to think about it again without seeing our actor as Lincoln. Daniel is extraordinary in the role."

"Skyfall" took over the top spot at the weekend box office from Disney's animated comedy "Wreck-It Ralph," which fell to No. 2 with $33.1 million, raising its domestic total to $93.7 million.

While "Skyfall" marked a new high for Bond's opening-weekend revenue, the film has a long way to go to match the biggest audiences 007 has ever drawn. Adjusted for inflation, Sean Connery's 1965 Bond adventure "Thunderball" would have taken in an estimated $508 million domestically in today's dollars, with its 1964 predecessor "Goldfinger" not far behind at $444 million, according to box-office tracker Hollywood.com.

The Bond films over the last two decades have come in around the $200 million range domestically in inflation-adjusted dollars.

Still, Craig's Bond is setting a new critical standard for the franchise. While "Quantum of Solace" had a so-so critical reception, "Skyfall" and "Casino Royale" are among the best-reviewed Bond films, with critics and fans enjoying the darker edge Craig has imprinted on 007.

"'Skyfall' is to the Bond franchise what 'The Dark Knight' was to the Batman franchise," said Hollywood.com analyst Paul Dergarabedian. "By taking it to a whole other level, this is a different kind of Bond that can be taken really seriously."

Directed by Sam Mendes, the Academy Award-winning filmmaker behind "American Beauty" and Craig's director on "Road to Perdition," ''Skyfall" continues the current franchise's exploration into the emotional traumas that have shaped Bond's cool, aloof manner.

The film reveals secrets out of the past of Bond's boss, British spymaster M (Judi Dench), and pits 007 against a brilliant but unstable former agent (Javier Bardem) who's out for revenge.

Hollywood remains on a brisk pace this fall as the busy holiday season approaches. Overall domestic revenues totaled $172 million, up 26 percent from the same weekend last year, when "Immortals" led with $32.2 million.

For the year, domestic revenues are at $9.1 billion, up 4.3 percent from 2011's, according to Hollywood.com.

Estimated ticket sales for Friday through Sunday at U.S. and Canadian theaters, according to Hollywood.com. Where available, latest international numbers are also included. Final domestic figures will be released Monday.

1. "Skyfall," $87.8 million.

2. "Wreck-It Ralph," $33.1 million.

3. "Flight," $15.1 million.

4. "Argo," $6.7 million.

5. "Taken 2," $4 million.

6. "Here Comes the Boom," $2.6 million

7. "Cloud Atlas," $2.53 million.

8. "Pitch Perfect," $2.5 million.

9. "The Man with the Iron Fists," $2.49 million.

10. "Hotel Transylvania," $2.4 million.

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Estimated weekend ticket sales at international theaters (excluding the U.S. and Canada) for films distributed overseas by Hollywood studios, according to Rentrak:

1. "Skyfall," $89 million.

2. "Argo," $12 million.

3. "Wreck-It Ralph," $11.2 million.

4. "Hotel Transylvania," $11.1 million.

5. "A Werewolf Boy," $10.5 million.

6. "Cloud Atlas," $8.7 million.

7. "Paranormal Activity 4," $6 million.

8 (tie). "Asterlix and Obelix: God Save Britannia," $4.4 million.

8 (tie). "Confession of Murder," $4.4 million.

10. "Madagascar 3: Europe's Most Wanted," $4.1 million.

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Online:

http://www.hollywood.com

http://www.rentrak.com

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Universal and Focus are owned by NBC Universal, a unit of Comcast Corp.; Sony, Columbia, Sony Screen Gems and Sony Pictures Classics are units of Sony Corp.; Paramount is owned by Viacom Inc.; Disney, Pixar and Marvel are owned by The Walt Disney Co.; Miramax is owned by Filmyard Holdings LLC; 20th Century Fox and Fox Searchlight are owned by News Corp.; Warner Bros. and New Line are units of Time Warner Inc.; MGM is owned by a group of former creditors including Highland Capital, Anchorage Advisors and Carl Icahn; Lionsgate is owned by Lions Gate Entertainment Corp.; IFC is owned by AMC Networks Inc.; Rogue is owned by Relativity Media LLC.

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